Fbxw28 Gene Detail

Summary

• Symbol
  Fbxw28
• Name
  F-box and WD-40 domain protein 28
• Synonyms
  Gm9337

• Feature Type
  protein coding gene
• IDs
  MGI:3779847
  NCBI Gene: 668758
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr9:109151954-109168727 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, 59.64 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  192 from dbSNP Build 142
• Strain Annotations
  12

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3779847	protein coding gene	Chr9:109151862-109168727 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0035330	protein coding gene	Chr9:111278381-111610932 (-)
A/J	MGP_AJ_G0035311	protein coding gene	Chr9:107296941-107739653 (-)
AKR/J	MGP_AKRJ_G0035243	protein coding gene	Chr9:109952593-110156695 (-)
BALB/cJ	MGP_BALBcJ_G0035308	protein coding gene	Chr9:107033112-107425307 (-)
C3H/HeJ	MGP_C3HHeJ_G0035015	protein coding gene	Chr9:110416553-110611320 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0035826	protein coding gene	Chr9:114408683-114484391 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032719	protein coding gene	Chr9:104992181-104994762 (-)
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0034983	protein coding gene	Chr9:118592995-118728827 (-)
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0035218	protein coding gene	Chr9:111450680-112156831 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0035846	protein coding gene	Chr9:110321732-110384065 (-)
PWK/PhJ	MGP_PWKPhJ_G0034031	protein coding gene	Chr9:107201911-107329813 (-)
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  FBXW12, F-box and WD repeat domain containing 12

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FBXW12, F-box and WD repeat domain containing 12
  
• Synonyms
  FBW12, FBXO12, FBXO35
• Links
  HGNC:20729

  NCBI Gene ID: 285231

  neXtProt AC: NX_Q6X9E4

  UniProt: Q6X9E4

  
  
• Chr Location
  3p21.31; chr3:48372219-48401259 (+)  GRCh38

---

• MGI Vertebrate Homology
  Fbxw28 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: FBXW12
• Gene Tree
  Fbxw28
  

Mutations,
Alleles, and
Phenotypes

• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  24 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  2

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  36
• RefSeq
  6
• UniProt
  5
• CCDS
  CCDS52932.1, CCDS52933.1

• Ensembl
  ENSMUSG00000054087 (Evidence)
• NCBI Gene
  668758

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000054087	Ensembl Gene Model | MGI Sequence Detail	16774	C57BL/6J
transcript	ENSMUST00000112039	Ensembl | MGI Sequence Detail	1497	Not Applicable
polypeptide	ENSMUSP00000107670	Ensembl | MGI Sequence Detail	466	Not Applicable

Protein
Information

• UniProt
  5 Sequences
• InterPro Domains
  IPR001810 F-box domain
  IPR036047 F-box-like domain superfamily
  IPR052121 F-box Protein Family Substrate Recognition Components
  IPR036322 WD40-repeat-containing domain superfamily
  IPR015943 WD40/YVTN repeat-like-containing domain superfamily

Molecular
Reagents

• All nucleic 2

  cDNA 2

References

• Summaries
  All 10

  Gene Ontology 1
• Earliest
  J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
• Latest
  J:161428 Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas, Annotation inferences using phylogenetic trees. 2010;