Rpl35rt Gene Detail

Summary

• Symbol
  Rpl35rt
• Name
  ribosomal protein L35, retrotransposed
• Synonyms
  Gm2000

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:3780170
  NCBI Gene: 100038991
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr1:156193610-156194054 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, 67.71 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  121 from dbSNP Build 142
• Strain Annotations
  15

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3780170	protein coding gene	Chr1:156193610-156194054 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034263	protein coding gene	Chr8:127490676-127491118 (+)
A/J	MGP_AJ_G0034243	protein coding gene	Chr8:122233430-122233872 (+)
AKR/J	MGP_AKRJ_G0034170	protein coding gene	Chr8:125746757-125747323 (+)
BALB/cJ	MGP_BALBcJ_G0034236	protein coding gene	Chr8:122419711-122420153 (+)
C3H/HeJ	MGP_C3HHeJ_G0033947	protein coding gene	Chr8:126384664-126385106 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0034756	protein coding gene	Chr8:131771458-131771900 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0033920	protein coding gene	Chr8:136584204-136584646 (+)
DBA/2J	MGP_DBA2J_G0034076	protein coding gene	Chr8:121388781-121389223 (+)
FVB/NJ	MGP_FVBNJ_G0034020	protein coding gene	Chr8:120549921-120550363 (+)
LP/J	no annotation
NOD/ShiLtJ	MGP_NODShiLtJ_G0034067	protein coding gene	Chr8:138723413-138723855 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034775	protein coding gene	Chr8:125978019-125978461 (+)
PWK/PhJ	MGP_PWKPhJ_G0032976	protein coding gene	Chr8:121142812-121143742 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020959	protein coding gene	Chr15:81484689-81485133 (-)
WSB/EiJ	MGP_WSBEiJ_G0033391	protein coding gene	Chr8:126706704-126707098 (+)

Homology

• Human Ortholog
  RPL35, ribosomal protein L35

• Vertebrate Orthologs
  7

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  RPL35, ribosomal protein L35
  
• Synonyms
  DBA19, L35, uL29
• Links
  HGNC:10344

  NCBI Gene ID: 11224

  neXtProt AC: NX_P42766

  UniProt: P42766

  
  
• Chr Location
  9q33.3; chr9:124857880-124861981 (-)  GRCh38

---

• MGI Vertebrate Homology
  Rpl35rt stringent orthology
  1 human;1 mouse;5 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: RPL35
• Gene Tree
  Rpl35rt
  

Human Diseases

• Diseases
  1 with human RPL35 associations

				Human Disease	Mouse Models
				Diamond-Blackfan anemia 19 IDs Diamond-Blackfan anemia 19       DOID:0111886 OMIM:618312

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  2
• Genomic Mutations
  2 involving Rpl35rt
• Find Mice (IMSR)
  4 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  5
• GO References
  2

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  21
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000078193 (Evidence)
• NCBI Gene
  100038991

Representative Sequences			Length	Strain/Species
genomic	100038991	NCBI Gene Model | MGI Sequence Detail	445	C57BL/6J
polypeptide	Q6ZWV7	UniProt | EBI | MGI Sequence Detail	123	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• PDB
  6SWA, 7CPU, 7CPV, 7LS1, 7LS2
• InterPro Domains
  IPR001854 Large ribosomal subunit protein uL29
  IPR018254 Large ribosomal subunit protein uL29, conserved site
  IPR045059 Large ribosomal subunit protein uL29, eukaryotes
  IPR036049 Large ribosomal subunit protein uL29 superfamily

Other
Accession IDs

MGI:7481996

References

• Summaries
  All 10

  Gene Ontology 2

  Phenotypes 2
• Earliest
  J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
• Latest
  J:155856 The Gene Ontology Consortium, Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs. 2014;

TSS for Rpl35rt:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr9563	Chr1:156193607-156193614 (+)	1 bp