Sp110-ps1 MGI Mouse Pseudogene Detail - MGI:3783243 - Sp110 nuclear body protein, pseudogene 1

Sp110-ps1 Pseudogene Detail

Symbol

Sp110-ps1
Name

Sp110 nuclear body protein, pseudogene 1
Synonyms

Gm16026

Feature Type

pseudogene
IDs

MGI:3783243
NCBI Gene: 118567760
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr1:85250516-85254756 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 43.46 cM
Mapping Data

1 experiment

SNPs within 2kb

17 from dbSNP Build 142
Strain Annotations

5

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3783243	pseudogene	Chr1:85244419-85263212 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0036941	pseudogene	Chr1:78057905-78060847 (-)
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0039620	pseudogene	Chr1:87281464-87288313 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0039541	pseudogene	Chr1:95685821-95686966 (+)
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0038763	pseudogene	Chr1:85461566-85462458 (+)

Human Ortholog

SP110, SP110 nuclear body protein

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SP110, SP110 nuclear body protein
Synonyms

IFI41, IFI75, IPR1, VODI
Links

HGNC:5401

NCBI Gene ID: 3431

neXtProt AC: NX_Q9HB58

UniProt: Q9HB58
Chr Location

2q37.1; chr2:230165186-230225729 (-) GRCh38

MGI Vertebrate Homology

Sp110-ps1 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: SP110
Gene Tree

Sp110-ps1

Diseases

2 with human SP110 associations

				Human Disease	Mouse Models
				hepatic venoocclusive disease with immunodeficiency IDs hepatic venoocclusive disease with immunodeficiency DOID:0112254 MESH:C537257 OMIM:235550 ORDO:79124
				tuberculosis IDs tuberculosis DOID:399 DOID:10096 DOID:12688 DOID:12691 DOID:415 DOID:9901 DOID:9902 MESH:D014375 UMLS_CUI:C0041295

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

2
Chemically induced (other)

1
Radiation induced

1
Genomic Mutations

2 involving Sp110-ps1
Find Mice (IMSR)

0 strains or lines available

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706

Tissue x Stage Matrix

Other Mouse Links

Expression Atlas

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All Sequences

16
RefSeq

3

Ensembl

ENSMUSG00000079455 (Evidence)
NCBI Gene

118567760

			Length	Strain/Species	Flank
genomic	118567760	NCBI Gene Model \| MGI Sequence Detail	4241	C57BL/6J	± kb
transcript	XR_004936211	RefSeq \| MGI Sequence Detail	452	C57BL/6J
polypeptide	XP_036011764	RefSeq \| MGI Sequence Detail	144	C57BL/6J

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Microarray probesets 2

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MGI:3779372, MGI:3779374, MGI:7526678

Summaries

All 12

Gene Ontology 1

Phenotypes 4
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:7938 Juriloff DM, et al., Genetic and developmental studies of a new mouse mutation that produces otocephaly. J Craniofac Genet Dev Biol. 1985;5(2):121-45

TSS for Sp110-ps1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr7660	Chr1:85250121-85250137 (+)	-387 bp
Tssr7661	Chr1:85254620-85254668 (+)	4,128 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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