Tg(CAG-Has2)99Nita
Transgene Detail

Summary

• Symbol: Tg(CAG-Has2)99Nita
• Name: transgene insertion 99, Naoki Itano
• MGI ID: MGI:3785859
• Synonyms: CAG-Neo-Has2, HA-99, Has2 cTg
• Transgene: Tg(CAG-Has2)99Nita Location: unknown
• Alliance: Tg(CAG-Has2)99Nita page

Transgene origin

• Strain of Origin: BALB/cCrSlc

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Has2)99Nita expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Has2 (MGI:107821)

• Mutation details: The CAG promoter (chicken beta actin promoter) was used to drive ubiquitous expression of a flag-tagged Has2 cDNA preceded by a floxed neo cassette with a polyadenylation sequence. Cre-mediated recombination is required to remove the neo cassette and allow for Has2 expression. Seven lines were established with line HA-99 examined further. (J:118655)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:118655 Koyama H, et al., Hyperproduction of Hyaluronan in Neu-Induced Mammary Tumor Accelerates Angiogenesis through Stromal Cell Recruitment: Possible Involvement of Versican/PG-M. Am J Pathol. 2007 Mar;170(3):1086-99
• All: 5 reference(s)