In(10)17Rk Cytogenetic Marker Detail

Summary

• Symbol
  In(10)17Rk
• Name
  inversion, Chr 10, Roderick 17
• Synonyms
  Hmga2^pg-J, In17Rk, pygmy Jackson

• Feature Type
  chromosomal inversion
• IDs
  MGI:3790438

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 10, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotypes from 1 allele in 1 genetic background
  5 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (other)
  1
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for this inversion are small and sterile. The phenotype is similar to the pygmy mutation and is attributable to the location of the distal inversion breakpoint in the Hmga2 gene.

References

• Summaries
  All 6

  Phenotypes 5
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:74548 Benson KF, et al., Molecular Characterization of the Mouse In(10)17Rk Inversion and Identification of a Novel Muscle-Specific Gene at the Proximal Breakpoint. Genetics. 2002 Jan;160(1):279-87