Tg(Igh-3/Igh-6VD93)1241Ust
Transgene Detail

Summary

• Symbol: Tg(Igh-3/Igh-6VD93)1241Ust
• Name: transgene insertion 1241 Ursula Storb
• MGI ID: MGI:3793439
• Synonyms: g2b-mumem, Tg(g2b/mumem)3Storb, Tg(Igh)Bri128
• Transgene: Tg(Igh-3/Igh-6VD93)1241Ust Location: unknown
• Alliance: Tg(Igh-3/Igh-6VD93)1241Ust page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igh-3/Igh-6VD93)1241Ust expresses 2 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ighg2b (MGI:96445)
  mouse	Ighm (MGI:96448)

• Mutation details: The transgene construct consists of the variable and constant regions from mouse gamma2b (Igh-3) clone (VD93) fused to membrane exons from the mu (Igh-6) gene (2.6kb fragment from pVH176mu). (J:135209)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:135209 Roth PE, et al., Immunoglobulin gamma 2b transgenes inhibit heavy chain gene rearrangement, but cannot promote B cell development. J Exp Med. 1993 Dec 1;178(6):2007-21
• All: 4 reference(s)