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Altre Gene Detail
Summary
  • Symbol
    Altre
  • Name
    aging liver Treg-expressed non-protein coding RNA
  • Synonyms
    Gm16157
  • Feature Type
    lncRNA gene
  • IDs
    MGI:3801721
    NCBI Gene: 100504026
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:67916087-67926342 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 37.49 cM
Strain
Comparison
more
  • SNPs within 2kb
    391 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3801721
 lncRNA gene Chr7:67916087-67926342 (-)
129S1/SvImJ MGP_129S1SvImJ_G0007189
 lincRNA gene Chr7:69575131-69587852 (-)
A/J MGP_AJ_G0007185
 lincRNA gene Chr7:68119882-68133723 (-)
AKR/J MGP_AKRJ_G0007155
 lincRNA gene Chr7:69560725-69575082 (-)
BALB/cJ MGP_BALBcJ_G0007164
 lincRNA gene Chr7:67863206-67877045 (-)
C3H/HeJ MGP_C3HHeJ_G0007107
 lincRNA gene Chr7:70272423-70284394 (-)
C57BL/6NJ MGP_C57BL6NJ_G0007333
 lincRNA gene Chr7:72514668-72527947 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006542
 lincRNA gene Chr7:70968380-70978760 (-)
CAST/EiJ MGP_CASTEiJ_G0007009
 lincRNA gene Chr7:60947393-60959109 (-)
CBA/J MGP_CBAJ_G0007090
 lincRNA gene Chr7:74792085-74806857 (-)
DBA/2J MGP_DBA2J_G0007111
 lincRNA gene Chr7:66825577-66835522 (-)
FVB/NJ MGP_FVBNJ_G0007134
 lincRNA gene Chr7:66949320-66959502 (-)
LP/J MGP_LPJ_G0007193
 lincRNA gene Chr7:70784444-70794401 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0007111
 lincRNA gene Chr7:74991516-75006705 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0007336
 lincRNA gene Chr7:68946685-68957924 (-)
PWK/PhJ MGP_PWKPhJ_G0006952
 lincRNA gene Chr7:59888918-59900384 (-)
SPRET/EiJ MGP_SPRETEiJ_G0006860
 lincRNA gene Chr7:55976048-55988911 (-)
WSB/EiJ MGP_WSBEiJ_G0007071
 lincRNA gene Chr7:69276251-69287987 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Aged male mice with loss of expression in regulatory T cells display reduced survival, increased liver tumor incidence and regulatory T cell abnormalities.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      27
    • RefSeq
      2
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100504026 NCBI Gene Model | MGI Sequence Detail 10256 C57BL/6J ±  kb
    transcript NR_040340 RefSeq | MGI Sequence Detail 1147 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5
    Other
    Accession IDs
    less
    MGI:7444229
    References
    more
    • Summaries
      All 21
      Phenotypes 13
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:342907 Ding C, et al., A T(reg)-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver. Nat Aging. 2023 Jul;3(7):813-828
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory