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Il11ra3 Gene Detail
Summary
  • Symbol
    Il11ra3
  • Name
    interleukin 11 receptor subunit alpha 3
  • Synonyms
    Gm13305, Gm2002
  • Feature Type
    protein coding gene
  • IDs
    MGI:3801997
    NCBI Gene: 100042555
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:42158842-42168603 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 22.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3801997
 protein coding gene Chr4:42158842-42168603 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0028133
 protein coding gene Chr4:38220576-38226471 (+)
AKR/J MGP_AKRJ_G0028095
 protein coding gene Chr4:39211799-39236818 (+)
BALB/cJ MGP_BALBcJ_G0028138
 protein coding gene Chr4:38469226-38569215 (+)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027328
 protein coding gene Chr4:39453901-39457866 (+)
CBA/J MGP_CBAJ_G0027838
 protein coding gene Chr4:42524227-42604247 (+)
DBA/2J MGP_DBA2J_G0027982
 protein coding gene Chr4:38084370-38153897 (+)
FVB/NJ MGP_FVBNJ_G0027949
 protein coding gene Chr4:37404340-37474244 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IL11RA, interleukin 11 receptor subunit alpha
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IL11RA, interleukin 11 receptor subunit alpha
  • Synonyms
    CRSDA
  • Links
    NCBI Gene ID: 3590
    neXtProt AC: NX_Q14626
    UniProt: Q14626

  • Chr Location
    9p13.3; chr9:34652162-34661902 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100042555 NCBI Gene Model | MGI Sequence Detail 9762 C57BL/6J ±  kb
transcript NM_001099348 RefSeq | MGI Sequence Detail 1953 Not Specified  
polypeptide P70225 UniProt | EBI | MGI Sequence Detail 432 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003961 Fibronectin type III
    IPR036116 Fibronectin type III superfamily
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR003530 Long hematopoietin receptor, soluble alpha chain, conserved site
    IPR050379 Type I Cytokine Receptor
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:3780172, MGI:7525398
References
more
  • Summaries
    All 16
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:239582 Mouse Genome Informatics Scientific Curators, Mouse Contig Sequence-to-Marker Association Load. 2017;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory