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Sap25 Gene Detail
Summary
  • Symbol
    Sap25
  • Name
    sin3 associated polypeptide
  • Synonyms
    25 kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:3802945
    NCBI Gene: 751865
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137639735-137641164 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 76.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3802945
 protein coding gene Chr5:137639596-137641164 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030238
 protein coding gene Chr5:142418467-142420035 (+)
A/J MGP_AJ_G0030206
 protein coding gene Chr5:136206996-136208563 (+)
AKR/J MGP_AKRJ_G0030139
 protein coding gene Chr5:140635747-140637312 (+)
BALB/cJ MGP_BALBcJ_G0030216
 protein coding gene Chr5:137581465-137583032 (+)
C3H/HeJ MGP_C3HHeJ_G0029932
 protein coding gene Chr5:141288422-141289989 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030668
 protein coding gene Chr5:147679439-147681007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027886
 protein coding gene Chr5:130449835-130451400 (+)
CAST/EiJ MGP_CASTEiJ_G0029342
 protein coding gene Chr5:140689615-140691179 (+)
CBA/J MGP_CBAJ_G0029902
 protein coding gene Chr5:153553420-153554987 (+)
DBA/2J MGP_DBA2J_G0030053
 protein coding gene Chr5:136108238-136109805 (+)
FVB/NJ MGP_FVBNJ_G0030008
 protein coding gene Chr5:135315904-135317471 (+)
LP/J MGP_LPJ_G0030142
 protein coding gene Chr5:142890685-142892252 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030040
 protein coding gene Chr5:156368978-156370545 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030709
 protein coding gene Chr5:140486612-140488180 (+)
PWK/PhJ MGP_PWKPhJ_G0029055
 protein coding gene Chr5:135199002-135200565 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028891
 protein coding gene Chr5:138055502-138057069 (+)
WSB/EiJ MGP_WSBEiJ_G0029415
 protein coding gene Chr5:141217581-141219149 (+)



Homology
more
  • Human Ortholog
    SAP25, Sin3A associated protein 25
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SAP25, Sin3A associated protein 25
  • Links
    NCBI Gene ID: 100316904
    neXtProt AC: NX_Q8TEE9
    UniProt: Q8TEE9

  • Chr Location
    chr7:100572228-100573900 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 751865 NCBI Gene Model | MGI Sequence Detail 1430 C57BL/6J ±  kb
transcript NM_001081962 RefSeq | MGI Sequence Detail 1079 C57BL/6  
polypeptide Q1EHW4 UniProt | EBI | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 5
    Other 2
References
more
  • Summaries
    All 13
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:105563 Shiio Y, et al., Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex. Mol Cell Biol. 2006 Feb;26(4):1386-97
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory