Tg(Myh6-Tnnt2*)1Feah
Transgene Detail

Summary

• Symbol: Tg(Myh6-Tnnt2*)1Feah
• Name: transgene insertion 1, Fehaan Ahmad
• MGI ID: MGI:3805021
• Synonyms: TG^K210delta
• Transgene: Tg(Myh6-Tnnt2*)1Feah Location: unknown
• Alliance: Tg(Myh6-Tnnt2*)1Feah page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Tnnt2*)1Feah expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tnnt2 (MGI:104597)

• Mutation details: The Myh6 promoter was used to drive cardiac-specific expression of an Tnnt2 cDNA containing nucleotide deletions that lead to the exclusion of lysine at position 210. This mutation mimics one found in patients with dilated cardiomyopathy. Four lines were generated with similar phenotype. No line numbers were given. (J:137964)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:137964 Ahmad F, et al., The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. PLoS One. 2008;3(7):e2642
• All: 1 reference(s)