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Ermardl1 Gene Detail
Summary
  • Symbol
    Ermardl1
  • Name
    ER membrane associated RNA degradation like 1
  • Synonyms
    Gm3435
  • Feature Type
    protein coding gene
  • IDs
    MGI:3810125
    NCBI Gene: 100041621
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr17:15230438-15242711 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 8.95 cM
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3810125
 protein coding gene Chr17:15230102-15242711 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ERMARD, ER membrane associated RNA degradation
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERMARD, ER membrane associated RNA degradation
  • Synonyms
    C6orf70, dJ266L20.3, PVNH6
  • Links
    NCBI Gene ID: 55780
    neXtProt AC: NX_Q5T6L9
    UniProt: Q5T6L9

  • Chr Location
    6q27; chr6:169751306-169781600 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ERMARD associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000116895 Ensembl Gene Model | MGI Sequence Detail 12274 C57BL/6J ±  kb
transcript ENSMUST00000097395 Ensembl | MGI Sequence Detail 1684 Not Applicable  
polypeptide ENSMUSP00000095007 Ensembl | MGI Sequence Detail 438 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR025209 Domain of unknown function DUF4209
    IPR039635 Endoplasmic reticulum membrane-associated RNA degradation protein
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
Other
Accession IDs
less
MGI:7447211
References
more
  • Summaries
    All 11
    Phenotypes 2
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory