Tg(tetO-TAg,CMV-rtTA)123Yihu
Transgene Detail

Summary

• Symbol: Tg(tetO-TAg,CMV-rtTA)123Yihu
• Name: transgene insertion 123, Yinghe Hu
• MGI ID: MGI:3819437
• Synonyms: pTRE-SV40Tag/pTet-on
• Transgene: Tg(tetO-TAg,CMV-rtTA)123Yihu Location: unknown
• Alliance: Tg(tetO-TAg,CMV-rtTA)123Yihu page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Transactivator)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: Two constructs, one containing the SV40 large T antigen (TAg) gene driven by the tetracycline responsive promoter element and the other containing the tetracycline responsive transactivator driven by the cytomegalovirus promoter, were co-injected into fertilized oocytes. Two lines (line 123 and line 144) were created. (J:141623)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:141623 Sun Q, et al., Involvement of insulin-like growth factor-insulin receptor signal pathway in the transgenic mouse model of medulloblastoma. Cancer Sci. 2008 Feb;99(2):234-40
• All: 1 reference(s)