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M14104Asr Gene Detail
Summary
  • Symbol
    M14104Asr
  • Name
    mutation 14104, Apurva K Srivastava
  • Synonyms
    14104
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3819960
  • Alliance
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 11, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for a mutation in this gene display reduced bone cross sectional area and increased volumetric bone density.
References
more
  • Summaries
    All 2
    Phenotypes 2
  • Earliest
    J:141536 Mohan S, et al., A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways. Bone. 2008 Feb;42(2):388-95
  • Latest
    J:220657 Edderkaoui B, et al., ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size. Physiol Genomics. 2013 Dec 15;45(24):1222-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory