Tg(YAC18)18Hay
Transgene Detail

Summary

• Symbol: Tg(YAC18)18Hay
• Name: transgene insertion 18, Michael Hayden
• MGI ID: MGI:3829789
• Transgene: Tg(YAC18)18Hay Location: unknown
• Alliance: Tg(YAC18)18Hay page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(YAC18)18Hay expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HTT (3064)

  Htt	(MGI:96067)

• Mutation details: A YAC containing a full-length human huntingtin gene was used to generate transgenic mice. The endogenous human HTT promoter directed expression in many tissues with levels in the brain and testes being the highest. (J:55405)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:55405 Hodgson JG, et al., A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron. 1999 May;23(1):181-92
• All: 18 reference(s)