Naa12 MGI Mouse Gene Detail - MGI:3833940 - N(alpha)-acetyltransferase 12, NatA catalytic subunit

Symbol

Naa12
Name

N(alpha)-acetyltransferase 12, NatA catalytic subunit
Synonyms

Gm16286

Feature Type

protein coding gene
IDs

MGI:3833940
NCBI Gene: 117903916
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr18:80250041-80255949 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 18, 53.34 cM

SNPs within 2kb

338 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3833940	protein coding gene	Chr18:80249980-80255956 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024591	protein coding gene	Chr18:81113989-81119992 (+)
A/J	MGP_AJ_G0024558	protein coding gene	Chr18:77559156-77565124 (+)
AKR/J	MGP_AKRJ_G0024529	protein coding gene	Chr18:79885793-79891989 (+)
BALB/cJ	MGP_BALBcJ_G0024556	protein coding gene	Chr18:77745438-77751406 (+)
C3H/HeJ	MGP_C3HHeJ_G0024325	protein coding gene	Chr18:79968628-79974604 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025003	protein coding gene	Chr18:83196583-83202559 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022434	protein coding gene	Chr18:76415877-76421870 (+)
CAST/EiJ	MGP_CASTEiJ_G0023798	protein coding gene	Chr18:80301619-80307591 (+)
CBA/J	MGP_CBAJ_G0024295	protein coding gene	Chr18:86226876-86232852 (+)
DBA/2J	MGP_DBA2J_G0024425	protein coding gene	Chr18:77113010-77118986 (+)
FVB/NJ	MGP_FVBNJ_G0024391	protein coding gene	Chr18:76432423-76438391 (+)
LP/J	MGP_LPJ_G0024509	protein coding gene	Chr18:80984118-80990121 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024421	protein coding gene	Chr18:87465379-87471347 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025052	protein coding gene	Chr18:80026471-80032667 (+)
PWK/PhJ	MGP_PWKPhJ_G0023543	protein coding gene	Chr18:77508405-77515280 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023349	protein coding gene	Chr18:80205010-80210950 (+)
WSB/EiJ	MGP_WSBEiJ_G0023860	protein coding gene	Chr18:79978806-79984774 (+)

Human Ortholog

NAA11, N-alpha-acetyltransferase 11, NatA catalytic subunit

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

NAA11, N-alpha-acetyltransferase 11, NatA catalytic subunit
Synonyms

ARD1B, ARD2, hARD2
Links

HGNC:28125

NCBI Gene ID: 84779

neXtProt AC: NX_Q9BSU3

UniProt: Q9BSU3
Chr Location

4q21.21; chr4:79155376-79326061 (-) GRCh38

MGI Vertebrate Homology

Naa12 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: NAA11
Gene Tree

Naa12

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Phenotype Summary

3 phenotype references

All Mutations and Alleles

4
Endonuclease-mediated

1
Targeted

2
Transposon induced

1
Genomic Mutations

1 involving Naa12
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

10 strains or lines available

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All GO Annotations

10
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

735
Tissues

5
cDNA Data

4
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Expression Atlas

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All Sequences

58
RefSeq

2
UniProt

1

Ensembl

ENSMUSG00000024571 (Evidence)
NCBI Gene

117903916

			Length	Strain/Species	Flank
genomic	117903916	NCBI Gene Model \| MGI Sequence Detail	5909	C57BL/6J	± kb
transcript	NM_001384178	RefSeq \| MGI Sequence Detail	1657	ZRU/MplStud
polypeptide	NP_001371107	RefSeq \| MGI Sequence Detail	220	ZRU/MplStud

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UniProt

1 Sequence

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All nucleic 6

cDNA 5

Primer pair 1

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MGI:6505483

Summaries

All 13

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 3
Earliest

J:308825 Kweon HY, et al., Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway. Elife. 2021 Aug 6;10:e65952

TSS for Naa12:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr152093	Chr18:80249990-80250096 (+)	2 bp
Tssr152094	Chr18:80250102-80250115 (+)	68 bp
Tssr152095	Chr18:80250386-80250433 (+)	369 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24