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Tg(RP23-65I14)2Jno
Transgene Detail
Summary
Symbol: Tg(RP23-65I14)2Jno
Name: transgene insertion 2, Jeffrey L Noebels
MGI ID: MGI:3842799
Synonyms: alpha1G-Tg2
Transgene: Tg(RP23-65I14)2Jno  Location: unknown  
Alliance: Tg(RP23-65I14)2Jno page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(RP23-65I14)2Jno expresses 3 genes
 
Mutation detailsThis transgene consists of the mouse BAC RP23-65114 (GenBank id AL64596) containing the full coding sequence for Cacna1g, Abcc3, and Ankrd40 along with the 5' end of 330000P08Rik and the 3' end of Spata20. This line has over 10 transgene copy integrations. Overexpression of Cacna1g in the brain was verified by quantitative RT-PCR and western blot analysis. (J:146431)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:146431 Ernst WL, et al., Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy. J Neurosci. 2009 Feb 11;29(6):1615-25
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory