Tg(TXNRD2,COMT,ARVCF)1Nhir
Transgene Detail

Summary

• Symbol: Tg(TXNRD2,COMT,ARVCF)1Nhir
• Name: transgene insertion 1, Noboru Hiroi
• MGI ID: MGI:4358257
• Transgene: Tg(TXNRD2,COMT,ARVCF)1Nhir Location: unknown
• Alliance: Tg(TXNRD2,COMT,ARVCF)1Nhir page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(TXNRD2,COMT,ARVCF)1Nhir expresses 3 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ARVCF (421)

  Arvcf

  (MGI:109620)

  human

  COMT (1312)

  Comt	(MGI:88470)

  human

  TXNRD2 (10587)

  Txnrd2

  (MGI:1347023)

• Mutation details: The transgenic construct consists of a bacterial artificial chromosome (BAC) clone 467.8 encoding a 190 kb segment from human 22q11.2 including TXNRD2, COMT, and ARVCF. Transgenic mice were generated by microinjection into FVB mouse embryos. Mice have one to two copies of the transgene. (J:152368)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:152368 Suzuki G, et al., Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Hum Mol Genet. 2009 Oct 15;18(20):3914-25
• All: 1 reference(s)