Dp(7Herc2-Mkrn3)1Taku Cytogenetic Marker Detail

Summary

• Symbol
  Dp(7Herc2-Mkrn3)1Taku
• Name
  duplication, Chr 7, Toru Takumi 1

• Feature Type
  chromosomal duplication
• IDs
  MGI:4359727

Location &
Maps

• Sequence Map
  Chr7:55699944-62069887 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, Syntenic

Human Diseases

• Diseases
  1 with Dp(7Herc2-Mkrn3)1Taku mouse models

Human Disease

Mouse Models

autism spectrum disorder

IDs

autism spectrum disorder      

DOID:0060041
MESH:D000067877

View 3 models

Mouse Models

Human Disease Modeled: autism spectrum disorder

Allelic Composition	Genetic Background	Reference	Phenotypes
Dp(7Herc2-Mkrn3)1Taku/0	B6J.129S7-Dp(7Herc2-Mkrn3)1Taku	J:225285	View
Dp(7Herc2-Mkrn3)1Taku/0	involves: 129S7/SvEvBrd * C57BL/6	J:151648	View
Dp(7Herc2-Mkrn3)1Taku/0	involves: 129S7/SvEvBrd * C57BL/6J	J:190050	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  3 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  19 phenotypes from 1 allele in 3 genetic backgrounds
  18 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 18

  Diseases 3

  Phenotypes 18
• Earliest
  J:151648 Nakatani J, et al., Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism. Cell. 2009 Jun 26;137(7):1235-46
• Latest
  J:335224 Nakai N, et al., Virtual reality-based real-time imaging reveals abnormal cortical dynamics during behavioral transitions in a mouse model of autism. Cell Rep. 2023 Mar 24;:112258