Lmr21 QTL Detail

Summary

• Symbol
  Lmr21
• Name
  leishmaniasis resistance 21

• Feature Type
  QTL
• IDs
  MGI:4360533
• Candidate Genes
  1 Gene

Location &
Maps

• Sequence Map
  Chr7:127967235-127967336 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 1

  Phenotypes 1
• Earliest
  J:152405 Kurey I, et al., Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics. 2009 Sep;61(9):619-33

Candidate Genes for Lmr21:

Gene	Genome Location (GRCm39)	Reference	QTL Note
Il4ra	Chr7:125151443-125178646 (+)	J:152405	A potential candidated gene mapping near Lmr21, Lmr21a and Lmr21b which mapped to D7Mit67 at 63.5 cM on Chromosome 7 of CcS11/Dem in this study is: Il4ra, interleukin 4 receptor, alpha at 62.0 cM. [Table 9.] Possibly related QTL controlling other infections and co-localizing with the Lmr21 QTL are: Tria4, T cell receptor induced activation 4 at 46.0 cM; Heal6, wound healing/regeneration 6 at 52.4 cM; Tsiq1, T cell secretion of IL4 QTL 1 at 59.0 cM; and Dice2, determination of interleukin 4 commitment 2 at 63.5 cM [Table 10.]