Lmr23 QTL Detail

Summary

• Symbol
  Lmr23
• Name
  leishmaniasis resistance 23

• Feature Type
  QTL
• IDs
  MGI:4360535
• Candidate Genes
  8 Genes

Location &
Maps

• Sequence Map
  Chr16:12674057-12674200 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 1

  Phenotypes 1
• Earliest
  J:152405 Kurey I, et al., Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics. 2009 Sep;61(9):619-33

Candidate Genes for Lmr23:

Gene	Genome Location (GRCm39)	Reference	QTL Note
Igl-C5	Chr16, Syntenic	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]
Iglc1	Chr16:18880502-18880821 (-)	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]
Iglc3	Chr16:18884115-18884431 (-)	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]
Igll1	Chr16:16678535-16681849 (-)	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]
Iglv1	Chr16:18903767-18904210 (-)	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]
Iglv2	Chr16:19079153-19079594 (-)	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]
Vpreb1a	Chr16:16686265-16687119 (-)	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]
Vpreb1b	Chr16:17798292-17799137 (+)	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]