Tg(GHRL-TAg)3-1Hiwa
Transgene Detail

Summary

• Symbol: Tg(GHRL-TAg)3-1Hiwa
• Name: transgene insertion 3-1, Hiroshi Iwakura
• MGI ID: MGI:4360904
• Synonyms: GP-Tag
• Transgene: Tg(GHRL-TAg)3-1Hiwa Location: unknown
• Alliance: Tg(GHRL-TAg)3-1Hiwa page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: 4.085 Kb of the human promoter was used to drive expression of the SV40 large T antigen in ghrelin-expressing cells. Three lines were established (lines 1-5, 3-1, and 4-3). (J:152492)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Phenotypic Similarity to Human Syndrome: Ghrelinoma (J:152492)

References

• Original: J:152492 Iwakura H, et al., A mouse model of ghrelinoma exhibited activated growth hormone-insulin-like growth factor I axis and glucose intolerance. Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E802-11
• All: 1 reference(s)