Tg(Cd4-Il7r)1Wjl
Transgene Detail
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Symbol: |
Tg(Cd4-Il7r)1Wjl |
Name: |
transgene insertion 1, Warren J Leonard |
MGI ID: |
MGI:4415298 |
Synonyms: |
Tg IL-7Ralpha |
Transgene: |
Tg(Cd4-Il7r)1Wjl Location: unknown
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Alliance: |
Tg(Cd4-Il7r)1Wjl page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Cd4-Il7r)1Wjl expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Il7r (MGI:96562) |
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Mutation details: Transgenic mice express a murine Il7r cDNA under the control of a CD4 enhancer/promoter, which lacks the CD4 silencer located in intron 1 and thus directs transgene expression in T lineage cells.
(J:131561)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:131561 Haring JS, et al., Constitutive Expression of IL-7 Receptor {alpha} Does Not Support Increased Expansion or Prevent Contraction of Antigen-Specific CD4 or CD8 T Cells following Listeria monocytogenes Infection. J Immunol. 2008 Mar 1;180(5):2855-62 |
All: |
2 reference(s) |
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