Tg(CD2-Tcra,Cd4-Tcrb)4CKang
Transgene Detail
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Symbol: |
Tg(CD2-Tcra,Cd4-Tcrb)4CKang |
Name: |
transgene insertion 4C, Sang-Mo Kang |
MGI ID: |
MGI:4415814 |
Synonyms: |
4C TCR |
Transgene: |
Tg(CD2-Tcra,Cd4-Tcrb)4CKang Location: unknown
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Alliance: |
Tg(CD2-Tcra,Cd4-Tcrb)4CKang page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(CD2-Tcra,Cd4-Tcrb)4CKang expresses
2 genes
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Mutation details: This transgene results from the coinjection of two constructs derived from a C57BL/6 hybridoma cell line responsive to BALB/c splenocytes. The Tcra construct under the control of the human CD2 promoter contains a cDNA including V alpha 8.5 sequence and the Tcrb construct under the control of the mouse Cd4 promoter (without the intronic silencer) contains a cDNA including V beta 13 sequence.
(J:155848)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:155848 Brennan TV, et al., A new T-cell receptor transgenic model of the CD4+ direct pathway: level of priming determines acute versus chronic rejection. Transplantation. 2008 Jan 27;85(2):247-55 |
All: |
16 reference(s) |
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