Tg(Ebf2-EGFP/icre)1Ggc
Transgene Detail

Summary

• Symbol: Tg(Ebf2-EGFP/icre)1Ggc
• Name: transgene insertion 1, Giacomo Consalez
• MGI ID: MGI:4421668
• Synonyms: Ebf2-Cre, Ebf2::Cre, Ebf2-iCre, Tg(Ebf2-Egfp-icre)1Ggc
• Transgene: Tg(Ebf2-EGFP/icre)1Ggc Location: unknown
• Alliance: Tg(Ebf2-EGFP/icre)1Ggc page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Ebf2-EGFP/icre)1Ggc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ebf2 (MGI:894332)

• Mutation details: The BAC clone RP24-283N8 containing 32 kb of 5'flanking sequence plus the first 6 exons of the murine Ebf2 gene was modified to insert the cDNA encoding a fusion of EGFP and the improved cre recombinase (icre) followed by the SV40 polyA signal into the first coding exon of Ebf2. This modified BAC was microinjected into the pronuclei of FVB/N oocytes. Founders were isolated and a line was established. The icre transcript distribution recapitulates that of endogenous Ebf2 transcripts at all locations and stages assayed. (J:156632)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ebf2 (mouse) Summary of all recombinase alleles driven by Ebf2. Comparative matrix view of recombinase activities Alliance mouse Ebf2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:156632 Chung SH, et al., Purkinje cell phenotype restricts the distribution of unipolar brush cells. Neuroscience. 2009 Dec 29;164(4):1496-508
• All: 4 reference(s)