Tg(CAG-SYVN1)1Tn
Transgene Detail

Summary

• Symbol: Tg(CAG-SYVN1)1Tn
• Name: transgene insertion 1, Toshihiro Nakajima
• MGI ID: MGI:4421708
• Transgene: Tg(CAG-SYVN1)1Tn Location: unknown
• Alliance: Tg(CAG-SYVN1)1Tn page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-SYVN1)1Tn expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SYVN1 (84447)

  Syvn1

  (MGI:1921376)

• Mutation details: This transgene contains the human synoviolin gene with a Flag tag at the 5' end under the control of the CMV early enhancer/chicken beta actin promoter. The expressed Flag-tagged protein is observed in every tissue, including synovial tissue, bone, cartilage, bone marrow, skin, vessels, and adipose tissue. (J:86009)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:86009 Amano T, et al., Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy. Genes Dev. 2003 Oct 1;17(19):2436-49
• All: 1 reference(s)