Tg(tetO-Notch4*)1Rwng
Transgene Detail

Summary

• Symbol: Tg(tetO-Notch4*)1Rwng
• Name: transgene insertion 1, Rong Wang
• MGI ID: MGI:4431198
• Synonyms: TRE-int3
• Transgene: Tg(tetO-Notch4*)1Rwng Location: unknown
• Alliance: Tg(tetO-Notch4*)1Rwng page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Notch4*)1Rwng expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Notch4 (MGI:107471)

• Mutation details: DNA encoding amino acids 1411-1964 of Notch4 was placed under the control of the tetracycline response element. (J:99859)

Disease models

Expression

In Structures Affected by this Mutation:

13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:99859 Carlson TR, et al., Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9884-9
• All: 6 reference(s)