p23-ST1 Gene Detail

Summary

• Symbol
  p23-ST1
• Name
  p23-ST1

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:4439296
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 4, Syntenic

Human Diseases

• Diseases
  1 with p23-ST1 mouse models

Human Disease

Mouse Models

normal pressure hydrocephalus

IDs

normal pressure hydrocephalus      

DOID:1572
ICD10CM:G91.2
MESH:D006850
OMIM:236690
UMLS_CUI:C0020258

View 1 model

Mouse Models

Human Disease Modeled: normal pressure hydrocephalus

Allelic Composition	Genetic Background	Reference	Phenotypes
p23-ST1/p23-ST1	C57BL/6J-p23-ST1	J:158278	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  17 phenotypes from 1 allele in 1 genetic background
  6 images
  2 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (ENU)
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for the ENU mutation exhibit normal-pressure hydrocephalus with astrocytosis, microgliosis, impaired coordination, abnormal urination, and deficits in short-term and long-term memory.

References

• Summaries
  All 2

  Diseases 1

  Phenotypes 2
• Earliest
  J:87589 Wu JY, et al., ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. J Clin Invest. 2004 Feb;113(3):434-40
• Latest
  J:158278 Lee MJ, et al., Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus. PLoS One. 2009;4(11):e7868