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Ighv1-77 Gene Detail
Summary
  • Symbol
    Ighv1-77
  • Name
    immunoglobulin heavy variable 1-77
  • Synonyms
    Gm16746
  • Feature Type
    gene segment
  • IDs
    MGI:4439670
    NCBI Gene: 619994
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:115825487-115825780 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    244 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439670
 gene segment Chr12:115825487-115825975 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000096
 gene segment Chr12:118781663-118782149 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0000102
 gene segment Chr12:117956804-117957290 (-)
BALB/cJ MGP_BALBcJ_G0000090
 gene segment Chr12:114915215-114915701 (-)
C3H/HeJ MGP_C3HHeJ_G0000095
 gene segment Chr12:118226815-118227107 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000137
 gene segment Chr12:122406974-122407462 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0000106
 gene segment Chr12:112070276-112070763 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0000089
 gene segment Chr12:112548055-112548347 (-)
LP/J MGP_LPJ_G0000107
 gene segment Chr12:118874474-118874960 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0000092
 gene segment Chr12:108594723-108595210 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0000100
 gene segment Chr12:118083423-118083910 (-)



Homology
more
  • Human Ortholog
    IGHV1-45, immunoglobulin heavy variable 1-45
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV1-45, immunoglobulin heavy variable 1-45
  • Synonyms
    IGHV145, VH
  • Links
    NCBI Gene ID: 28466
    UniProt: A0A0A0MS14

  • Chr Location
    14q32.33; chr14:106506996-106507491 (-)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    21
  • RefSeq
    1
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 619994 NCBI Gene Model | MGI Sequence Detail 294 C57BL/6J ±  kb
transcript AF045501 GenBank | ENA | DDBJ | MGI Sequence Detail 417 C57BL/6  
polypeptide A0A0G2JGS9 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 6
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory