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Trbc1 Gene Detail
Summary
  • Symbol
    Trbc1
  • Name
    T cell receptor beta, constant region 1
  • Synonyms
    Gm16802, Tcrb-C1
  • Feature Type
    gene segment
  • IDs
    MGI:4439726
    NCBI Gene: 100125262
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:41515153-41516599 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 19.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    158 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439726
 gene segment Chr6:41515152-41516815 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002423
 gene segment Chr6:40045595-40048741 (+)
A/J MGP_AJ_G0002398
 gene segment Chr6:38299762-38301403 (+)
AKR/J MGP_AKRJ_G0002384
 gene segment Chr6:39538030-39540953 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0002371
 gene segment Chr6:39568885-39570750 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002519
 gene segment Chr6:41059842-41061505 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0002333
 gene segment Chr6:39372143-39373794 (+)
CBA/J MGP_CBAJ_G0002363
 gene segment Chr6:42764950-42769084 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0002423
 gene segment Chr6:40055280-40056963 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002352
 gene segment Chr6:44998623-45001275 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002513
 gene segment Chr6:39514912-39516575 (+)
PWK/PhJ MGP_PWKPhJ_G0002295
 gene segment Chr6:37750924-37752808 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002247
 gene segment Chr6:39132549-39134207 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TRB, T cell receptor beta locus
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRB, T cell receptor beta locus
  • Synonyms
    TCRB, TRB@
  • Links
    NCBI Gene ID: 6957
    UniProt: P0DSE2, P0DTU4

  • Chr Location
    7q34; chr7:142299011-142813287 (+)  GRCh38
  • Human Ortholog
    TRBC1, T cell receptor beta constant 1
  • Synonyms
    BV05S1J2.2, TCRB, TCRBC1
  • Links
    NCBI Gene ID: 28639
    UniProt: P01850

  • Chr Location
    7q34; chr7:142791694-142793368 (+)  GRCh38
  • Human Ortholog
    TRBC2, T cell receptor beta constant 2
  • Synonyms
    TCRBC2
  • Links
    NCBI Gene ID: 28638
    UniProt: A0A5B9

  • Chr Location
    7q34; chr7:142801041-142802748 (+)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    19
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 100125262 NCBI Gene Model | MGI Sequence Detail 1447 C57BL/6J ±  kb
polypeptide A0A0A6YWV4 UniProt | EBI | MGI Sequence Detail 173 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050380 Immune Recognition and Response Modulators
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
References
more
  • Summaries
    All 8
    Gene Ontology 1
  • Earliest
    J:7518 Gascoigne NR, et al., Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes. Nature. 1984 Aug 2-8;310(5976):387-91
  • Latest
    J:167272 Parenti R, et al., Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity. Glia. 2010 Oct;58(13):1594-609
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory