Tg(Myh6-Tnf)1.6Amf
Transgene Detail

Summary

• Symbol: Tg(Myh6-Tnf)1.6Amf
• Name: transgene insertion 1.6, Arthur M Feldman
• MGI ID: MGI:4450947
• Synonyms: TNF1.6
• Transgene: Tg(Myh6-Tnf)1.6Amf Location: unknown
• Alliance: Tg(Myh6-Tnf)1.6Amf page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Tnf)1.6Amf expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tnf (MGI:104798)

• The mouse promoter drives cardiac expression of the mouse cDNA. Several lines were established. (J:109157)

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:104759 Saba S, et al., Atrial contractile dysfunction, fibrosis, and arrhythmias in a mouse model of cardiomyopathy secondary to cardiac-specific overexpression of tumor necrosis factor-{alpha}. Am J Physiol Heart Circ Physiol. 2005 Oct;289(4):H1456-67
• All: 26 reference(s)