Tg(Myh6-STK4)28Jusa
Transgene Detail

Summary

• Symbol: Tg(Myh6-STK4)28Jusa
• Name: transgene insertion 28, Junichi Sadoshima
• MGI ID: MGI:4452338
• Synonyms: Tg-Mst1, Tg(Myh6-MST1)28Jusa
• Transgene: Tg(Myh6-STK4)28Jusa Location: unknown
• Alliance: Tg(Myh6-STK4)28Jusa page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-STK4)28Jusa expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  STK4 (6789)

  Stk4	(MGI:1929004)

• Mutation details: The mouse promoter drives cardiac-specific expression of the human cDNA. Two lines were created (line 28 and 8) with line 28 exhibiting high levels of expression and line 8 intermediate levels of expression. (J:139414)

Disease models

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:139414 Yamamoto S, et al., Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. J Clin Invest. 2003 May;111(10):1463-74
• All: 15 reference(s)