Tg(KRT5-AR)191Cct
Transgene Detail

Summary

• Symbol: Tg(KRT5-AR)191Cct
• Name: transgene insertion 191, Catherine C Thompson
• MGI ID: MGI:4818964
• Synonyms: K5-hAR
• Transgene: Tg(KRT5-AR)191Cct Location: unknown
• Alliance: Tg(KRT5-AR)191Cct page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT5-AR)191Cct expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AR (367)

  Ar	(MGI:88064)

• Tg(KRT5-AR)191Cct expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  KRT5 (3852)

  Krt5	(MGI:96702)

• Mutation details: The human promoter drives skin-specific expression of the human cDNA. Two lines were created (lines 191 and 335). Expression is detected in the nuclei of outer root sheath and basal epidermis. (J:159989)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:159989 Crabtree JS, et al., A mouse model of androgenetic alopecia. Endocrinology. 2010 May;151(5):2373-80
• All: 1 reference(s)