Del(7Gabrb3-Ube3a)1Yhj Cytogenetic Marker Detail

Summary

• Symbol
  Del(7Gabrb3-Ube3a)1Yhj
• Name
  deletion, Chr 7, Yong-hui Jiang 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:4830894

Location &
Maps

• Sequence Map
  Chr7:57240266-58956481 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, Syntenic

Human Diseases

• Diseases
  1 with Del(7Gabrb3-Ube3a)1Yhj mouse models

Human Disease

Mouse Models

Angelman syndrome

IDs

Angelman syndrome      

DOID:1932
ICD10CM:Q93.51
MESH:D017204
NCI:C75462
OMIM:105830
UMLS_CUI:C0162635

View 1 model

Mouse Models

Human Disease Modeled: Angelman syndrome

Allelic Composition	Genetic Background	Reference	Phenotypes
Del(7Gabrb3-Ube3a)1Yhj/+	B6.129S7-Del(7Gabrb3-Ube3a)1Yhj	J:164010	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  14 phenotypes from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Diseases 1

  Phenotypes 3
• Earliest
  J:164010 Jiang YH, et al., Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. PLoS One. 2010;5(8)
• Latest
  J:247640 Shi SQ, et al., Ube3a imprinting impairs circadian robustness in Angelman syndrome models. Curr Biol. 2015 Mar 02;25(5):537-45