Tg(Myh6-Nox4)3Jusa
Transgene Detail

Summary

• Symbol: Tg(Myh6-Nox4)3Jusa
• Name: transgene insertion 3, Junichi Sadoshima
• MGI ID: MGI:4834487
• Transgene: Tg(Myh6-Nox4)3Jusa Location: unknown
• Alliance: Tg(Myh6-Nox4)3Jusa page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Nox4)3Jusa expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Nox4 (MGI:1354184)

• The Myh6 promoter drives the expression of Nox4. Line 3 results in 1.3 fold overexpression. (J:164275)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:164275 Ago T, et al., Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circ Res. 2010 Apr 16;106(7):1253-64
• All: 2 reference(s)