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Rr7 Other Genome Feature Detail
Summary
  • Symbol
    Rr7
  • Name
    regulatory region 7
  • Synonyms
    CD8/LCR
  • Feature Type
    locus control region
  • IDs
    MGI:4837099
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 6, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 5 alleles in 4 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted mutation exhibit disregulation of Cd8a and Cd8b expression.
References
more
  • Summaries
    All 3
    Phenotypes 2
  • Earliest
    J:164573 Menzel U, et al., Replication allows inactivation of a knocked-in locus control region in inappropriate cell lineages. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16928-33
  • Latest
    J:179326 Menzel U, et al., Modulation of the murine CD8 gene complex following the targeted integration of human CD2-locus control region sequences. J Immunol. 2011 Oct 1;187(7):3712-20
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory