Tg(Eno2-TOR1A*)13Shas
Transgene Detail

Summary

• Symbol: Tg(Eno2-TOR1A*)13Shas
• Name: transgene insertion 13, Pullani Shashidharan
• MGI ID: MGI:4838202
• Synonyms: NSE-deltaE-torsinA
• Transgene: Tg(Eno2-TOR1A*)13Shas Location: unknown
• Alliance: Tg(Eno2-TOR1A*)13Shas page

Transgene origin

• Strain of Origin: (C57BL/6J x C3H)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-TOR1A*)13Shas expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TOR1A (1861)

  Tor1a

  (MGI:1353568)

• Mutation details: The rat promoter drives neuron-specific expression of the human cDNA containing a deletion of GAG (encoding glutamic acid). Lines 13, 22, 35, and 49 were generated. (J:95447)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:95447 Shashidharan P, et al., Transgenic mouse model of early-onset DYT1 dystonia. Hum Mol Genet. 2005 Jan 1;14(1):125-33
• All: 2 reference(s)