Gdac1 QTL Detail

Summary

• Symbol
  Gdac1
• Name
  glutathione peroxidase deficiency associated colitis 1

• Feature Type
  QTL
• IDs
  MGI:4838413

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:171572 Esworthy RS, et al., Colitis locus on chromosome 2 impacting the severity of early-onset disease in mice deficient in GPX1 and GPX2. Inflamm Bowel Dis. 2011 Jun;17(6):1373-86
• Latest
  J:236000 Esworthy RS, et al., The Gdac1 locus modifies spontaneous and Salmonella-induced colitis in mice deficient in either Gpx2 or Gpx1 gene. Free Radic Biol Med. 2013 Dec;65:1273-83