Tg(Sox3)1Pqt
Transgene Detail

Summary

• Symbol: Tg(Sox3)1Pqt
• Name: transgene insertion 1, Paul Q Thomas
• MGI ID: MGI:4839388
• Synonyms: Sox3 transgene sex reversed, SR, Tg(Sox3-EGFP)SrPqt
• Transgene: Tg(Sox3)1Pqt Location: unknown Genetic Position: Chr19, Syntenic
• Alliance: Tg(Sox3)1Pqt page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Sox3)1Pqt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sox3 (MGI:98365)

• Mutation details: Two copies of the transgene, comprising approximately 36 kb of genomic sequence from the Sox3 locus followed by an internal ribosomal entry site (IRES) and a cDNA encoding enhanced green fluorescent protein (EGFP), have integrated into Chr 19 at bands B/C1, upstream of the aldehyde dehydrogenase superfamily 1, subfamily A1 gene. (J:171839)
• Inheritance: Not Specified

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:171839 Sutton E, et al., Identification of SOX3 as an XX male sex reversal gene in mice and humans. J Clin Invest. 2011 Jan 4;121(1):328-41
• All: 2 reference(s)