Actc1dt MGI Mouse Gene Detail - MGI:4844008 - actin, alpha, cardiac muscle 1 divergent transcript

Symbol

Actc1dt
Name

actin, alpha, cardiac muscle 1 divergent transcript
Synonyms

C130080G10Rik

Feature Type

lncRNA gene
IDs

MGI:4844008
NCBI Gene: 100303644
Alliance

gene page
Transcription Start Sites

20 TSS

Sequence Map

Chr2:113884877-113891986 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 57.55 cM

SNPs within 2kb

272 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4844008	lncRNA gene	Chr2:113884816-113895349 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0003617	antisense lncRNA gene	Chr2:116530423-116540810 (+)
A/J	MGP_AJ_G0003599	antisense lncRNA gene	Chr2:111798847-111820786 (+)
AKR/J	MGP_AKRJ_G0003577	antisense lncRNA gene	Chr2:114900395-114921198 (+)
BALB/cJ	MGP_BALBcJ_G0003588	antisense lncRNA gene	Chr2:112024496-112037688 (+)
C3H/HeJ	MGP_C3HHeJ_G0003535	antisense lncRNA gene	Chr2:115325631-115337019 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0003727	antisense lncRNA gene	Chr2:120385579-120395976 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0003235	antisense lncRNA gene	Chr2:106956363-106968705 (+)
CAST/EiJ	MGP_CASTEiJ_G0003498	antisense lncRNA gene	Chr2:115629713-115642483 (+)
CBA/J	MGP_CBAJ_G0003532	antisense lncRNA gene	Chr2:124603391-124615762 (+)
DBA/2J	MGP_DBA2J_G0003540	antisense lncRNA gene	Chr2:111244946-111255896 (+)
FVB/NJ	MGP_FVBNJ_G0003560	antisense lncRNA gene	Chr2:110101524-110116915 (+)
LP/J	MGP_LPJ_G0003617	antisense lncRNA gene	Chr2:116832879-116847638 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0003548	antisense lncRNA gene	Chr2:128979566-128993905 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0003728	antisense lncRNA gene	Chr2:114974666-114988928 (+)
PWK/PhJ	MGP_PWKPhJ_G0003453	antisense lncRNA gene	Chr2:110761024-110772389 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0003396	antisense lncRNA gene	Chr2:114132284-114146809 (+)
WSB/EiJ	MGP_WSBEiJ_G0003532	antisense lncRNA gene	Chr2:115799090-115810491 (+)

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Gene Tree

Actc1dt

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Phenotype Summary

6 phenotypes from 1 allele in 1 genetic background
5 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Chemically induced (other)

1
Gene trapped

1
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Actc1dt
Find Mice (IMSR)

0 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Homozygous null mice show increased cardiomyocyte proliferation in postnatal and adult hearts and protection from myocardial infraction-induced injury.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

7

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas

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All Sequences

33
RefSeq

1

Ensembl

ENSMUSG00000092397 (Evidence)
NCBI Gene

100303644

Representative Sequences				Length	Strain/Species	Flank
	genomic	100303644	NCBI Gene Model \| MGI Sequence Detail	7110	C57BL/6J	± kb
	transcript	NR_028422	RefSeq \| MGI Sequence Detail	1909	C57BL/6

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All nucleic 7

cDNA 7

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MGI:7567981

Summaries

All 10

Phenotypes 5
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:297375 Ponnusamy M, et al., Long Noncoding RNA CPR (Cardiomyocyte Proliferation Regulator) Regulates Cardiomyocyte Proliferation and Cardiac Repair. Circulation. 2019 Jun 4;139(23):2668-2684

TSS for Actc1dt:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr19440	Chr2:113884777-113884784 (+)	-96 bp
Tssr19441	Chr2:113884810-113884821 (+)	-61 bp
Tssr19442	Chr2:113884825-113884834 (+)	-47 bp
Tssr19443	Chr2:113884843-113884866 (+)	-22 bp
Tssr19444	Chr2:113884872-113884896 (+)	7 bp
Tssr19445	Chr2:113884897-113884942 (+)	43 bp
Tssr19446	Chr2:113885115-113885126 (+)	244 bp
Tssr19447	Chr2:113885330-113885341 (+)	459 bp
Tssr19448	Chr2:113885616-113885625 (+)	744 bp
Tssr19449	Chr2:113885630-113885642 (+)	759 bp
Tssr19450	Chr2:113885643-113885663 (+)	776 bp
Tssr19451	Chr2:113885671-113885690 (+)	804 bp
Tssr19452	Chr2:113885699-113885708 (+)	827 bp
Tssr603	Chr2:113885737-113885747 (+)	865 bp
Tssr19453	Chr2:113885751-113885768 (+)	883 bp
Tssr19454	Chr2:113885779-113885793 (+)	909 bp
Tssr19455	Chr2:113885805-113885808 (+)	930 bp
Tssr19456	Chr2:113886765-113886809 (+)	1,910 bp
Tssr19457	Chr2:113891644-113891657 (+)	6,774 bp
Tssr19458	Chr2:113891665-113891676 (+)	6,794 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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