Tg(Lck-TNFSF13)3919Mhah
Transgene Detail

Summary

• Symbol: Tg(Lck-TNFSF13)3919Mhah
• Name: transgene insertion 3919, Michael Hahne
• MGI ID: MGI:4850020
• Synonyms: APRIL-Tg
• Transgene: Tg(Lck-TNFSF13)3919Mhah Location: unknown
• Alliance: Tg(Lck-TNFSF13)3919Mhah page

Transgene origin

• Strain of Origin: BALB/c and C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-TNFSF13)3919Mhah expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TNFSF13 (8741)

  Tnfsf13

  (MGI:1916833)

• Mutation details: The mouse promoter drives B cell-specific expression of the human cDNA. Lines 3919 and 3923 were generated. (J:77325)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:77325 Stein JV, et al., APRIL modulates B and T cell immunity. J Clin Invest. 2002 Jun;109(12):1587-98
• All: 11 reference(s)