Rr9 Other Genome Feature Detail

Summary

• Symbol
  Rr9
• Name
  regulatory region 9
• Synonyms
  CGRE

• Feature Type
  transcription factor binding site
• IDs
  MGI:4880761

Location &
Maps

• Sequence Map
  Chr11:53526886-53527279 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:167446 homology arm edges: chr11:53526886-53527279

• Genetic Map
  Chromosome 11, Syntenic

Strain
Comparison

• SNPs within 2kb
  87 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  4 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for a knock-out allele exhibit reduced IL13 production.

References

• Summaries
  All 5

  Phenotypes 4
• Earliest
  J:167446 Tanaka S, et al., The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells. Nat Immunol. 2011 Jan;12(1):77-85
• Latest
  J:254605 Motomura Y, et al., Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation. Immunity. 2014 May 15;40(5):758-71