Tg(Cd4-Zbtb16)1797Aben
Transgene Detail

Summary

• Symbol: Tg(Cd4-Zbtb16)1797Aben
• Name: transgene insertion 1797, Albert Bendelac
• MGI ID: MGI:4881493
• Synonyms: CD4p-PLZF
• Transgene: Tg(Cd4-Zbtb16)1797Aben Location: unknown
• Alliance: Tg(Cd4-Zbtb16)1797Aben page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cd4-Zbtb16)1797Aben expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Zbtb16 (MGI:103222)

• Mutation details: The CD4-PLZF transgene was designed with murine CD4 promoter/enhancer and intronic silencer elements driving expression of the zinc finger and BTB domain containing 16 (Zbtb16 or PLZF) gene. Line 1797 was established. (J:139690)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Transgenic lines were derived from two transgenic founder mice and designated line 1797 and line 1960. No apparent differences were observed between the two lines.

References

• Original: J:139690 Savage AK, et al., The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity. 2008 Sep;29(3):391-403
• All: 9 reference(s)