Tg(Defa2-Myd88)1Lvh
Transgene Detail
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Symbol: |
Tg(Defa2-Myd88)1Lvh |
Name: |
transgene insertion 1, Lora Hooper |
MGI ID: |
MGI:4941629 |
Synonyms: |
Cr2-FlagMyd88 |
Transgene: |
Tg(Defa2-Myd88)1Lvh Location: unknown
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Alliance: |
Tg(Defa2-Myd88)1Lvh page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Defa2-Myd88)1Lvh expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Myd88 (MGI:108005) |
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Mutation details: FLAG-tagged Myd88 was placed under the transcriptional control of nucleotides -6500 to +134 of the mouse Defa2 (defensin, alpha, 2; also known as cryptdin 2) gene. Human growth hormone (hGH, +3 to +2150) was placed immediately downstream to enhance transgenic expression, but is not transcribed.
(J:169662)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:169662 Vaishnava S, et al., Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20858-63 |
All: |
1 reference(s) |
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