Tg(Lck-Tnfsf15,-EGFP)#Targ
Transgene Detail

Summary

• Symbol: Tg(Lck-Tnfsf15,-EGFP)#Targ
• Name: transgene insertion, Stephan R Targan
• MGI ID: MGI:4943308
• Synonyms: LCK-CD2-Tl1A-GFP Tg
• Transgene: Tg(Lck-Tnfsf15,-EGFP)#Targ Location: unknown
• Alliance: Tg(Lck-Tnfsf15,-EGFP)#Targ page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Lck-Tnfsf15,-EGFP)#Targ expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tnfsf15 (MGI:2180140)

• Mutation details: The proximal Lck promoter and CD2 enhancer drives T cell-specific expression of the mouse cDNA and IRES-EGFP. Eight lines were generated. The pound symbol (#) is used when no line is specifed and/or lines are pooled. (J:169462)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:169462 Shih DQ, et al., Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis. PLoS One. 2011;6(1):e16090
• All: 6 reference(s)