Krtap10-32 Gene Detail

Summary

• Symbol
  Krtap10-32
• Name
  keratin associated protein 10-32
• Synonyms
  Gm18596

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:5010781
  NCBI Gene: 100417409
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr10:77577813-77578334 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 39.72 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  108 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5010781	protein coding gene	Chr10:77577630-77578472 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  KRTAP10-1, keratin associated protein 10-1

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KRTAP10-1, keratin associated protein 10-1
  
• Synonyms
  KAP10.1, KAP18-1, KAP18.1, KRTAP10.1, KRTAP18-1, KRTAP18.1
• Links
  HGNC:22966

  NCBI Gene ID: 386677

  neXtProt AC: NX_P60331

  UniProt: P60331

  
  
• Chr Location
  21q22.3; chr21:44538981-44540195 (-)  GRCh38

---

• Human Ortholog
  KRTAP10-4, keratin associated protein 10-4
  
• Synonyms
  KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
• Links
  HGNC:20521

  NCBI Gene ID: 386672

  UniProt: P60372

  
  
• Chr Location
  21q22.3; chr21:44573729-44575371 (+)  GRCh38

---

• Human Ortholog
  KRTAP10-6, keratin associated protein 10-6
  
• Synonyms
  KAP10.6, KAP18.6, KRTAP18-6, KRTAP18.6
• Links
  HGNC:20523

  NCBI Gene ID: 386674

  neXtProt AC: NX_P60371

  UniProt: P60371

  
  
• Chr Location
  21q22.3; chr21:44591268-44592505 (-)  GRCh38

---

• MGI Vertebrate Homology
  Krtap10-32 stringent orthology
  3 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: KRTAP10-1, KRTAP10-4, KRTAP10-6
• Gene Tree
  Krtap10-32
  

Human Diseases

• References
  2 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  29 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Targeted
  3
• Genomic Mutations
  4 involving Krtap10-32
• Find Mice (IMSR)
  4 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  7
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000112864 (Evidence)
• NCBI Gene
  100417409

Representative Sequences			Length	Strain/Species
genomic	100417409	NCBI Gene Model | MGI Sequence Detail	522	C57BL/6J
polypeptide	A0A1W2P860	UniProt | EBI | MGI Sequence Detail	280	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR002494 Keratin-associated protein

Other
Accession IDs

MGI:7580653

References

• Summaries
  All 34

  Diseases 2

  Phenotypes 29
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:357279 Donovan MG, et al., Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome. Cell Rep. 2024 Aug 27;43(8):114599

TSS for Krtap10-32:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr98243	Chr10:77578512-77578517 (-)	-181 bp