Krtap10-33 Gene Detail

Summary

• Symbol
  Krtap10-33
• Name
  keratin associated protein 10-33
• Synonyms
  Gm19402

• Feature Type
  protein coding gene
• IDs
  MGI:5011587
  NCBI Gene: 100502831
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr10:77525791-77526591 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 39.72 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  117 from dbSNP Build 142
• Strain Annotations
  15

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5011587	protein coding gene	Chr10:77525791-77526644 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0017402	protein coding gene	Chr10:78033530-78034629 (-)
A/J	no annotation
AKR/J	MGP_AKRJ_G0017340	protein coding gene	Chr10:77321374-77322483 (-)
BALB/cJ	MGP_BALBcJ_G0017339	protein coding gene	Chr10:75508033-75509132 (-)
C3H/HeJ	MGP_C3HHeJ_G0017163	protein coding gene	Chr10:77406874-77407973 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0017797	protein coding gene	Chr10:80774367-80775164 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015492	protein coding gene	Chr10:71798748-71799883 (-)
CAST/EiJ	MGP_CASTEiJ_G0016733	protein coding gene	Chr10:77771778-77772887 (-)
CBA/J	MGP_CBAJ_G0017135	protein coding gene	Chr10:83882889-83883998 (-)
DBA/2J	MGP_DBA2J_G0017240	protein coding gene	Chr10:74590147-74591126 (-)
FVB/NJ	MGP_FVBNJ_G0017232	protein coding gene	Chr10:73767106-73768155 (-)
LP/J	MGP_LPJ_G0017313	protein coding gene	Chr10:78493018-78494127 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017261	protein coding gene	Chr10:85912855-85913942 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017836	protein coding gene	Chr10:77405577-77408437 (-)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0016300	protein coding gene	Chr10:76665421-76666221 (-)
WSB/EiJ	no annotation

Homology

• Human Ortholog
  KRTAP10-4, keratin associated protein 10-4

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KRTAP10-4, keratin associated protein 10-4
  
• Synonyms
  KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
• Links
  HGNC:20521

  NCBI Gene ID: 386672

  UniProt: P60372

  
  
• Chr Location
  21q22.3; chr21:44573729-44575371 (+)  GRCh38

---

• Human Ortholog
  KRTAP10-6, keratin associated protein 10-6
  
• Synonyms
  KAP10.6, KAP18.6, KRTAP18-6, KRTAP18.6
• Links
  HGNC:20523

  NCBI Gene ID: 386674

  neXtProt AC: NX_P60371

  UniProt: P60371

  
  
• Chr Location
  21q22.3; chr21:44591268-44592505 (-)  GRCh38

---

• Human Ortholog
  KRTAP10-7, keratin associated protein 10-7
  
• Synonyms
  KAP10.7, KAP18.7, KRTAP18-7
• Links
  HGNC:22970

  NCBI Gene ID: 386675

  neXtProt AC: NX_P60409

  UniProt: P60409

  
  
• Chr Location
  21q22.3; chr21:44600597-44602174 (+)  GRCh38

---

• MGI Vertebrate Homology
  Krtap10-33 stringent orthology
  3 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: KRTAP10-4, KRTAP10-6, KRTAP10-7
• Gene Tree
  Krtap10-33
  

Human Diseases

• References
  2 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  29 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Targeted
  3
• Genomic Mutations
  4 involving Krtap10-33
• Find Mice (IMSR)
  6 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  22
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS56723.1

• Ensembl
  ENSMUSG00000095970 (Evidence)
• NCBI Gene
  100502831

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000095970	Ensembl Gene Model | MGI Sequence Detail	801	C57BL/6J
transcript	ENSMUST00000180297	Ensembl | MGI Sequence Detail	801	Not Applicable
polypeptide	ENSMUSP00000136066	Ensembl | MGI Sequence Detail	266	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR002494 Keratin-associated protein

Other
Accession IDs

MGI:7580654

References

• Summaries
  All 36

  Diseases 2

  Gene Ontology 1

  Phenotypes 29
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:357279 Donovan MG, et al., Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome. Cell Rep. 2024 Aug 27;43(8):114599

TSS for Krtap10-33:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr98240	Chr10:77526641-77526646 (-)	-53 bp