Mirc8 Complex/Cluster/Region Detail

Summary

• Symbol
  Mirc8
• Name
  microRNA cluster 8, including Mirlet7d, Mirlet7f-1, and Mirlet7a-1

• Feature Type
  complex/cluster/region
• IDs
  MGI:5049947
  NCBI Gene: 112935939
• Cluster Members
  Mirlet7d, Mirlet7f-1, Mirlet7a-1 (3 members)

Location &
Maps

• Sequence Map
  Chr13:48689488-48691748 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, Syntenic

Strain
Comparison

• SNPs within 2kb
  92 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Find Mice (IMSR)
  3 strains or lines available

Sequences &
Gene Models

• All Sequences
  3

• NCBI Gene
  112935939

Representative Sequences			Length	Strain/Species
transcript	AJ459692	GenBank | ENA | DDBJ | MGI Sequence Detail	22	Not Specified

Other Database
Links

miRBase

MI0000405, MI0000556, MI0000562

References

• Summaries
  All 10

  Phenotypes 6
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:358024 Erice PA, et al., Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORgammat. Elife. 2024 May 9;13

Mirc8 Cluster contains:

More Data for these features

Member	Feature Type	Location
Mirlet7d, microRNA let7d	miRNA gene	Chr13:48689488-48689590 (-)
Mirlet7f-1, microRNA let7f-1	miRNA gene	Chr13:48691305-48691393 (-)
Mirlet7a-1, microRNA let7a-1	miRNA gene	Chr13:48691655-48691748 (-)