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S2bpcox16 Gene Detail
Summary
  • Symbol
    S2bpcox16
  • Name
    synaptojanin 2 binding protein Cox16 readthrough
  • Synonyms
    Gm20498
  • Feature Type
    protein coding gene
  • IDs
    MGI:5141963
    NCBI Gene: 105940408
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:81405634-81579679 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 37.60 cM
Strain
Comparison
more
  • SNPs within 2kb
    2238 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5141963
 protein coding gene Chr12:81405626-81579685 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019899
 protein coding gene Chr12:81811395-82003347 (-)
A/J MGP_AJ_G0019857
 protein coding gene Chr12:78811102-79011232 (-)
AKR/J MGP_AKRJ_G0019832
 protein coding gene Chr12:80977534-81156496 (-)
BALB/cJ MGP_BALBcJ_G0019836
 protein coding gene Chr12:79051920-79237866 (-)
C3H/HeJ MGP_C3HHeJ_G0019642
 protein coding gene Chr12:81433683-81613463 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020288
 protein coding gene Chr12:84188030-84395210 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017907
 protein coding gene Chr12:75900587-75967819 (-)
CAST/EiJ MGP_CASTEiJ_G0019192
 protein coding gene Chr12:76301118-76496698 (-)
CBA/J MGP_CBAJ_G0019613
 protein coding gene Chr12:87453704-87660831 (-)
DBA/2J MGP_DBA2J_G0019728
 protein coding gene Chr12:78403547-78588625 (-)
FVB/NJ MGP_FVBNJ_G0019714
 protein coding gene Chr12:77240775-77437725 (-)
LP/J MGP_LPJ_G0019800
 protein coding gene Chr12:81708699-81912731 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019753
 protein coding gene Chr12:90451122-90669327 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020323
 protein coding gene Chr12:80493014-80685485 (-)
PWK/PhJ MGP_PWKPhJ_G0018958
 protein coding gene Chr12:72821101-72991246 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018752
 protein coding gene Chr12:75016721-75192241 (-)
WSB/EiJ MGP_WSBEiJ_G0019245
 protein coding gene Chr12:81136222-81333685 (-)



Homology
more
  • Human Ortholog
    SYNJ2BP, synaptojanin 2 binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYNJ2BP, synaptojanin 2 binding protein
  • Synonyms
    ARIP2, OMP25
  • Links
    NCBI Gene ID: 55333
    neXtProt AC: NX_P57105
    UniProt: P57105

  • Chr Location
    14q24.2; chr14:70366499-70417090 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021139 Ensembl Gene Model | MGI Sequence Detail 174046 C57BL/6J ±  kb
    transcript ENSMUST00000166664 Ensembl | MGI Sequence Detail 2284 Not Applicable  
    polypeptide ENSMUSP00000131728 Ensembl | MGI Sequence Detail 182 Not Applicable  
    For the selected sequence
    Other
    Accession IDs
    less
    MGI:7481234
    References
    more
    • Summaries
      All 14
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:76839 Matsuzaki T, et al., Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway. J Biol Chem. 2002 May 24;277(21):19008-18
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory