Tg(Myh6-Mtpn)4Ssen
Transgene Detail

Summary

• Symbol: Tg(Myh6-Mtpn)4Ssen
• Name: transgene insertion 4, Subha Sen
• MGI ID: MGI:5284885
• Synonyms: Myo-Tg
• Transgene: Tg(Myh6-Mtpn)4Ssen Location: unknown
• Alliance: Tg(Myh6-Mtpn)4Ssen page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Mtpn)4Ssen expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mtpn (MGI:99445)

• Mutation details: Transgene construct contains the mouse myotrophin (Mtpn) gene, under the direction of the mouse Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, promoter. Four lines were generated (line 1, 2, 3, and 4). (J:89823)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:89823 Sarkar S, et al., Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice. [RETRACTED]. J Biol Chem. 2004 May 7;279(19):20422-34
• All: 9 reference(s)