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Tg(Actb-GFP,-Bmp4)1Csk
Transgene Detail
Summary
Symbol: Tg(Actb-GFP,-Bmp4)1Csk
Name: transgene insertion 1, Chugai Pharmaceutical Co, Ltd
MGI ID: MGI:5291512
Synonyms: Tg(Actb-GFP-Bmp4)1Csk
Transgene: Tg(Actb-GFP,-Bmp4)1Csk  Location: unknown  
Alliance: Tg(Actb-GFP,-Bmp4)1Csk page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Actb-GFP,-Bmp4)1Csk expresses 1 gene
 
Mutation detailsA construct was generated by inserting an expression cassette with a floxed Renilla GFP cDNA and mouse polyA, followed by the full length murine Bmp4 cDNA, into an expression vector containing the cytomegalovirus enhancer/mouse beta-actin promoter and mouse beta-globin genomic DNA. This transgenic vector was injected into pronuclei of C57BL/6J oocytes. Lines 1 and 5 were established. (J:173500)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:173500 Tominaga T, et al., Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy. J Biol Chem. 2011 Jun 3;286(22):20109-16
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory